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Corporate Profile

Aeglea is a biotechnology company committed to developing enzyme-based therapeutics in the field of amino acid metabolism to treat rare genetic diseases and cancer. The company’s engineered human enzymes modulate the extremes of amino acid metabolism in the blood to reduce toxic levels of amino acids in inborn errors of metabolism or target tumor metabolism for cancer treatment. AEB1102, Aeglea’s lead product candidate, is currently being studied in two ongoing Phase 1 clinical trials in patients with advanced solid tumors and acute myeloid leukemia/myelodysplastic syndrome (AML/MDS). Additionally, Aeglea is recruiting patients into its Phase 1/2 trial of AEB1102 for the treatment of patients with Arginase I deficiency. The company is building a pipeline of additional product candidates targeting key amino acids, including AEB4104, which degrades homocystine, a target for an inborn error of metabolism, as well as two potential treatments for cancer, AEB3103, which degrades cysteine/cystine, and AEB2109, which degrades methionine.

Stock Information

AGLE (Common Stock)
ExchangeNASDAQ (US Dollar)
Price$5.22
Change (%) Stock is Up 0.25 (5.03%)
Volume53,102
As of 12/14/17 4:00 p.m. ET
Data provided by Nasdaq. Minimum 15 minutes delayed.
Stock chart for: AGLE.O.  Currently trading at $5.22 with a 52 week high of $8.14 and a 52 week low of $2.81.

Recent News

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12/07/17

Aeglea BioTherapeutics to Present at BMO Capital Markets Prescriptions for Success Healthcare Conference

Company to Webcast Presentation on Thursday, December 14 at 8:30 a.m. ET AUSTIN, Texas, Dec. 07, 2017 (GLOBE NEWSWIRE) -- Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE), a biotechnology company committed to the discovery and development of engineered

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11/29/17

Aeglea BioTherapeutics Doses First Pediatric Patient with Arginase 1 Deficiency in its Phase 1/2 Trial with Pegzilarginase (AEB1102)

Clinical Agreement Reached with FDA to Enable Pediatric Dosing AUSTIN, Texas, Nov. 29, 2017 (GLOBE NEWSWIRE) -- Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE), a biotechnology company committed to the discovery and development of engineered human enzy

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11/07/17

Aeglea BioTherapeutics Provides Corporate Update and Reports Third Quarter 2017 Financial Results

AUSTIN, Texas, Nov. 07, 2017 (GLOBE NEWSWIRE) -- Aeglea BioTherapeutics, Inc., (NASDAQ:AGLE) a biotechnology company committed to developing enzyme-based therapeutics in the field of amino acid metabolism to treat rare genetic diseases and cancer,

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