Investor FAQ

1.Where is Aeglea BioTherapeutics’ corporate headquarters?
2.Where is Aeglea BioTherapeutics incorporated?
3.When is Aeglea BioTherapeutics’ fiscal year-end?
4.How is Aeglea BioTherapeutics’ stock traded?
5.Who is Aeglea BioTherapeutics’ transfer agent?
6.How do I transfer stock, change the address on my shareholder account, or replace a lost stock certificate?
7.Who is Aeglea BioTherapeutics’ auditor?
8.How can I view documents Aeglea BioTherapeutics has filed with the Securities & Exchange Commission (SEC), including Forms 10-K and 10-Q?
9.Whom should I contact regarding investor inquiries?
1.Where is Aeglea BioTherapeutics’ corporate headquarters?
 Aeglea BioTherapeutics is headquartered at 901 South Mo Pac Expressway Ste. 250, Barton Oaks Plaza One, Austin, TX 78746.

2.Where is Aeglea BioTherapeutics incorporated?
 Aeglea BioTherapeutics is incorporated in the state of Delaware.

3.When is Aeglea BioTherapeutics’ fiscal year-end?
 Aeglea BioTherapeutics will end the fiscal year on December 31st.

4.How is Aeglea BioTherapeutics’ stock traded?
 Aeglea BioTherapeutics trades on the NASDAQ Global Market under the symbol “AGLE”.

5.Who is Aeglea BioTherapeutics’ transfer agent?
 Aeglea BioTherapeutics’ transfer agent is American Stock Transfer & Trust Company, LLC.

6.How do I transfer stock, change the address on my shareholder account, or replace a lost stock certificate?
 American Stock Transfer & Trust Company
(800) 937-5449 (Toll-free)
(718) 921-8124 (International)
http://www.amstock.com/new/InvestorServices/ShareholderServices.aspx

If delivering by mail:

American Stock Transfer & Trust Company Operations Center
Attn: Reorganization Department
P.O. Box 2042
New York, NY 10272-2042

If delivering by hand or courier:

American Stock Transfer & Trust Company
Operations Center
Attn: Reorganization Department
6201 15th Avenue
Brooklyn, NY 11219

7.Who is Aeglea BioTherapeutics’ auditor?
 Aeglea BioTherapeutics’s auditor is PricewaterhouseCoopers LLP, Austin, Texas.

8.How can I view documents Aeglea BioTherapeutics has filed with the Securities & Exchange Commission (SEC), including Forms 10-K and 10-Q?
 Aeglea BioTherapeutics SEC filings can be viewed on our SEC Filings page.

9.Whom should I contact regarding investor inquiries?
 You can submit queries to Aeglea BioTherapeutics investor relations department by contacting investors@aegleabio.com.