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Presentations

Date	Documents
Dec 03, 2019	Add Files Aeglea BioTherapeutics Corporate Presentation 2.9 MB

Past Events

Date	Title
Summary Toggle Oct 16-20, 2018	American Society of Human Genetics (ASHG) Annual Meeting Title #1: Improvements in Arginase 1 Deficiency-related disease manifestations following plasma arginine reduction with pegzilarginase: early Phase 2 results Title #2: Improved survival and amelioration of disease-related liver pathology in a mouse model of homocystinuria with a novel homocysteine degrading enzyme Title #3: Clinical features of Arginase 1 Deficiency: Review of Literature Case Series Supporting Materials Improvements in Arginase 1 Deficiency Related Disease Manifestations Following Plasma Arginine Reductions With Pegzilarginase: Early Phase 2 Results 1.3 MB Clinical Features of Arginase 1 Deficiency: Review of a Literature Case Series 1.1 MB Improved Survival & Amelioration of Disease-Related Liver Pathology in a Mouse Model of Homocystinuria with a Novel Homocysteine Degrading Enzyme 2 MB
Summary Toggle Oct 21, 2018 1:35 PM CDT	European Society for Medical Oncology (ESMO) 2018 Congress Title: Initial cohort expansion results of sustained arginine depletion with pegzilarginase in melanoma patients in a Phase 1 advanced solid tumor trial Supporting Materials Initial cohort expansion results of sustained arginine depletion with Pegzilarginase in melanoma patients in a phase 1 advanced solid tumor trial 1.2 MB
Summary Toggle Oct 26, 2018 5:54 PM PDT	American Society of Nephrology (ASN) Supporting Materials Enzymatic Degradation of Cystine Decreases Nephrolithiasis in a Mouse Model of Cystinuria 1.6 MB
Summary Toggle Nov 09, 2018	Japanese Society for Inherited Metabolic Diseases 2018 Annual Meeting Supporting Materials Clinical Features of Arginase 1 Deficiency: Review of Global Literature 1.5 MB
Summary Toggle Nov 09, 2018	Society for Immunotherapy of Cancer (SITC) 2018 Annual Meeting Supporting Materials Depletion of Plasma Arginine with Pegzilarginase (AEB1102) Enhances the Anti-Tumor Activity of Immune Checkpoint Inhibitors 1.7 MB
Summary Toggle Apr 07, 2019 4:00 PM PDT	Society for Inherited Metabolic Disorders (SIMD) Annual Meeting Location Bellevue, Washington Supporting Materials Sustained Reductions in Plasma Arginine Following Pegzilarginase Administration in Patients with Arginase-1 Deficiency are Accompanied by Improvements in Mobility and Adaptive Behavior 807 KB
Summary Toggle Sep 03, 2019 9:00 AM EDT	Society for the Study of Inborn Errors of Metabolism (SSIEM) Annual Symposium Location: Rotterdam, Netherlands Supporting Materials Randomised, double-blind, placebo-controlled phase 3 study to evaluate pegzilarginase in patients with arginase-1 deficiency 354.5 KB Sustained Lowering of High Plasma Arginine Levels in ARG1-D With Pegzilarginase is Accompanied by Improvements in Disease Manifestations 108.6 KB
Summary Toggle Nov 07, 2019	American Society of Nephrology Kidney Week Annual Meeting Supporting Materials Impact of Enzymatic Degradation of Plasma Cystine in a Mouse Model of Cystinuria Under Dehydration Challenge 903.3 KB
Summary Toggle Dec 03, 2019 8:45 AM EST	Evercore ISI HealthCONx Boston, MA Click here for webcast
Summary Toggle Dec 04, 2019 4:30 PM EST	Piper Jaffray Healthcare Conference New York, NY Click here for webcast